Fairbrother KJ, Heasman PA: Anticalculus agents. J Clin Periodontol ; the research associated with the development of anticalculus agents and to evalu-. Request PDF on ResearchGate | Anticalculus agents | Most dentifrices and some mouthrinses now contain 1 or more active anticalculus agents to achieve. With the help of antiplaque and anticalculus agents. Chemical plaque control – Rationale. Gingivitis & periodontitis are highly prevalent diseases and.

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The safe and effective amount of the compound or composition will vary with the particular condition being treated, ahents age and physical condition of the patient being treated, the severity of the condition, the duration of the treatment, the nature of concurrent therapy, the specific compound or composition employed, the particular pharmaceutically-acceptable carrier utilized, and like factors. Breath freshening and oral cleansing product with magnolia bark extract in combination with surface active agents.

Anticalculus agents for the treatment, control, and prevention of periodontal disease.

Suitable humectants for use in compositions of this invention include edible polyhydric alcohols such as glycerin, sorbitol, xylitol, polyethylene glycol, and propylene glycol, especially sorbitol and glycerin. The toxins in plaque and calculus can irritate the gingival tissues surrounding the coated teeth, causing inflammation and destruction of the gums which can lead to other complications.

Replacing the phosphate containing anticalculus agent with a phosphate-free anticalculus agent such as a zinc salt provides an oral care composition which has anticalculus properties and enhanced uptake of the antibacterial component. Following agitation, the mouthwash is typically expectorated from the oral cavity.

An oral-care composition comprising: If present, coloring agents typically are included at levels of from about 0. Following application, the toothpaste residue is typically removed from the tooth surface by using a liquid acceptable to the oral cavity, typically water, to rinse and be agnets from the oral cavity.


The liquid mouthwash is then agitated for from about 10 seconds to about 10 anticalculud. Surfactants may also be used as solubilizing agents to help retain sparingly soluble components, e. Today, we have many choices for anti-calculus strategy including pyrophosphates with or without Gantrez, zinc citrate, triclosan.

The preservatives prevent microbial growth in the compositions. It is difficult to predict the antiplaque efficacy of antibacterial compounds when incorporated in a delivery vehicle and particularly in oral compositions having other active ingredients, such as anticalculus tartar control agents.

Within anticakculus few hours of teeth cleaning, a film of salivary mucins, consisting primarily of proteins, forms on the teeth. Teeth are unique in the oral cavity because they have hard, non-shedding surfaces where bacteria and their products dental plaque can significantly accumulate, especially in approximal areas and along the gingival crevice.

It is intended to cover, in the appended claims, all such modifications that are within the scope of this invention.

An Overview on anticalculus agents – A review.

Periodontitis is a progressively worsened state of disease as compared to gingivitis. As plaque and calculus continue to build up, the gums begin to recede from the teeth and pockets form therebetween, which ultimately may result in destruction of the bone and periodontal ligament.

In mouthwashes, mouth rinses, mouth sprays and dental solutions, the preferred amount of pyro anion is from about 0. Delivery of the biphenol compound is typically measured using a model system of delivery to saliva-coated hydroxyapatite discs, as described in further detail below.

In one embodiment, it is present in the oral care composition in a concentration of about 0. Other preferred compositions of this invention are mouthwashes, mouth sprays, and dental solutions.


Request for preliminary examination filed prior to expiration of 19th month from priority date pct application filed before As used herein “formulation pH” means the anticalculu of the final composition. SUMMARY [] In a first aspect, the present invention provides an oral care composition for agenta or preventing calculus, which composition comprises an anticalculus agent and an antibacterial agent comprising a biphenol compound obtainable from Magnolia officinalis, wherein the composition is free of phosphate-containing anticalculus agents.


Summary of the Invention This invention involves oral-care compositions comprising: The silica abrasive can be precipitated silica or silica gels such as the silica xerogels described in U. The applicating device is then contacted with the oral cavity surfaces in a manner such avents the oral composition is contacted with tissue of the oral antifalculus, especially the teeth and gums.

For example, mouthrinses typically have a relatively low concentration of an active ingredient, as where dentifrices have a higher concentration to achieve the same delivered dosage based on ease of dispersion. Magnolol and honokiol are non-ionic hydroxybiphenyl compounds, the structures of which are represented as follows: Many of these suitable surfactants are disclosed in U. Nutrients can also be present in the oral qnticalculus of this invention, on condition that they are compatible with the Actives.

The silica abrasive polishing materials useful herein, as well ahents the other abrasives, generally have an average particle size ranging between about 0. All procedures are performed under room temperature, unless otherwise specified. Such mouthwashes and mouth sprays may also include an antiplaque agent from about 0.

Preferred pyro ions are pyrophosphate ions.